Substrate: E3 ubiquitin-protein ligase Nedd-4-like protein (Ubiquitin-protein ligase activity)
Seq-ID: Q8CFI0 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
acid-amino acid ligase activity,
sodium channel inhibitor activity,
protein binding		 cytoplasm protein modification process,
negative regulation of sodium ion transport
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 331 PPPPASPVSRTSPQELSEEVS - 17242355
HTP
0.71
 - -
0.89
 - low
S 475 LVEPQIRRPRSLSSPTVTLSA - 17114649
HTP
0.95
 - -
0.75
 - low
S 477 EPQIRRPRSLSSPTVTLSAPL - 17242355
HTP
1.00
 - -
0.75
 - low
S 477 EPQIRRPRSLSSPTVTLSAPL - 15958725
LTP
1.00
 - -
0.75
 - low
S 508 AVKDTLSNPQSPQPSPYNSPK - 17242355
HTP
0.92
 - -
0.89
 - low
S 512 TLSNPQSPQPSPYNSPKPQHK - 17242355
HTP
0.93
 - -
0.93
 - low

Substrate: E3 ubiquitin-protein ligase Nedd-4-like protein (Ubiquitin-protein ligase activity)
Seq-ID: Q96PU5 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-61615   SMAD2_HUMAN
MINT-63860   GDIR1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sodium channel regulator activity,
protein binding,
ubiquitin-protein ligase activity		 cytoplasm positive regulation of endocytosis,
water homeostasis,
excretion,
sodium ion transport,
interspecies interaction between organisms,
cellular sodium ion homeostasis,
regulation of protein catabolic process,
response to metal ion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 302 PPPPASPGSRTSPQELSEELS - 18669648
HTP
0.34
 - -
0.92
 - medium
T 318 SEELSRRLQITPDSNGEQFSS - 18669648
HTP
0.27
 - -
0.72
 - medium
S 342 REPSSRLRSCSVTDAVAEQGH SGK_group 12911626
LTP
0.96
 - -
0.73
 - medium
S 342 REPSSRLRSCSVTDAVAEQGH PKA_group 15328345
LTP
0.96
 - -
0.73
 - medium
S 342 REPSSRLRSCSVTDAVAEQGH SGK_group 16716084
LTP
0.96
 - -
0.73
 - medium
S 342 REPSSRLRSCSVTDAVAEQGH - 18669648
HTP
0.96
 - -
0.73
 - medium
T 367 SAPAGRARSSTVTGGEEPTPS PKA_group 15328345
LTP
0.04
 MOD_PKA_2
 - -
0.90
 - medium
T 367 SAPAGRARSSTVTGGEEPTPS SGK_group 15140763
LTP
0.04
 MOD_PKA_2
 - -
0.90
 - medium
S 446 LIEPQIRRPRSLSSPTVTLSA - 18669648
HTP
0.32
 - -
0.73
 - medium
S 448 EPQIRRPRSLSSPTVTLSAPL SGK_group 12911626
LTP
1.00
 - -
0.74
 - medium
S 448 EPQIRRPRSLSSPTVTLSAPL PKA_group 15328345
LTP
1.00
 - -
0.74
 - medium
S 448 EPQIRRPRSLSSPTVTLSAPL SGK_group 16716084
LTP
1.00
 - -
0.74
 - medium
S 448 EPQIRRPRSLSSPTVTLSAPL SGK_group 15677482
LTP
1.00
 - -
0.74
 - medium
S 448 EPQIRRPRSLSSPTVTLSAPL - 18669648
HTP
1.00
 - -
0.74
 - medium
S 449 PQIRRPRSLSSPTVTLSAPLE - 17081983
HTP
0.36
 - -
0.75
 - medium
S 449 PQIRRPRSLSSPTVTLSAPLE - 18669648
HTP
0.36
 - -
0.75
 - medium
T 451 IRRPRSLSSPTVTLSAPLEGA - 18669648
HTP
0.29
 - -
0.78
 - medium
S 464 LSAPLEGAKDSPVRRAVKDTL - 18669648
HTP
0.81
 - -
0.74
 - medium
S 479 AVKDTLSNPQSPQPSPYNSPK - 17081983
HTP
0.14
 - -
0.90
 - medium
S 479 AVKDTLSNPQSPQPSPYNSPK - 18669648
HTP
0.14
 - -
0.90
 - medium
S 483 TLSNPQSPQPSPYNSPKPQHK - 17081983
HTP
0.81
 - -
0.93
 - medium
S 483 TLSNPQSPQPSPYNSPKPQHK - 18669648
HTP
0.81
 - -
0.93
 - medium
S 487 PQSPQPSPYNSPKPQHKVTQS - 17081983
HTP
0.83
 - -
0.89
 - medium
S 487 PQSPQPSPYNSPKPQHKVTQS - 18669648
HTP
0.83
 - -
0.89
 - medium

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